FAQs About Enterosgel

What is Enterosgel?

Enterosgel is CE certified medical device that is composed of an organic mineral and water (70% Polymethylsiloxane polyhydrate and 30% Purified water). Enterosgel does not contain substances that can cause allergic or toxic reactions. It is free from preservatives, gluten, dairy, sugar, flavours or colouring and is suitable for vegans.

What is Enterosgel used to treat?

Enterosgel can treat acute (short-term) diarrhoea and irritable bowel syndrome with diarrhoea (IBS-D).

Acute diarrhoea includes gastroenteritis (tummy bugs), food poisoning, traveller’s diarrhoea, food allergies/intolerances, stress or hormone related diarrhoea. Enterosgel reduces the duration that the diarrhoea lasts and reduces the frequency of loose stools.

Irritable bowel syndrome with diarrhoea, has regular diarrhoea and other symptoms. Enterosgel relieves diarrhoea, abdominal pain, bloating, and urgency and also improves quality of life in people with IBS-D.

What is the evidence to support Enterosgel?

Enterosgel was developed in 1980’s and has been available as an over-the-counter treatment since 1996 in Europe. Since that time millions of people have used Enterosgel worldwide.

There is a lot of scientific evidence to support Enterosgel, there have been lab-based studies to show how it works by binding and removing harmful substances from the gut that can cause diarrhoea and other symptoms, in both short-term diarrhoea (acute) and also in people with IBS with diarrhoea (IBS-D).

Many clinical studies in both adults and children have shown that it is a safe and effective treatment. Two of these studies have been completed in the UK. The first was a randomised controlled trial investigating Enterosgel® for the treatment of acute diarrhoea in adults recruited from GP surgeries. This showed that Enterosgel significantly reduced the duration of diarrhoea in patients that either had a gastrointestinal infection or other causes for their short-term diarrhoea.

The second was a large UK trial of 440 patients and investigated the efficacy and safety of Enterosgel in the treatment of patients with IBS with diarrhoea (IBS-D). The results were published in a top medical journal and show that Enterosgel is a safe and effective treatment for the main IBS-D symptoms of; diarrhoea, abdominal pain, bloating, and urgency. After all trial patients tried Enterosgel during the open label phase, 76% of them said that it gave then adequate relief of their IBS symptoms.

Is Enterosgel a medicine?

No, Enterosgel is classified as a medical device and has a CE certificate for use in Europe. It is a medical device and not a medicine as Enterosgel is not absorbed into the bloodstream from the gut but travels along the inside of the gut removing harmful substances that cause symptoms before it is completely excreted with the stools. Enterosgel does not cause any systemic side effects.

Can I get Enterosgel from my doctor?

Enterosgel is available over-the-counter to buy from Pharmacies and health stores, it can also be prescribed by a doctor as it is listed in the medical device section of the NHS Drug Tariff.

Possible side effects of Enterosgel?

Enterosgel is a safe and drug free treatment with a brilliant safety history over 30 years and no reports of severe adverse events. There are no systemic side effects from taking Enterosgel. Uncommon side effects
are constipation or nausea, which can be also due to the underlining condition (e.g.
IBS, stomach or vomiting bugs).

During treatment of IBS diarrhoea stop taking Enterosgel if you do not have a bowel movement for 1-2 days and increase intake of water and continue the treatment after the next bowel movement.

How is Enterosgel different from other silica based intestinal adsorbents?

There are several different intestinal adsorbents based on the natural silica or clay. Enterosgel is based on pure organic mineral called methylsilicic acid. Enterosgel does not contain any preservatives and additives, which could cause allergic or toxic reactions. Enterosgel has an extensive body of post-marketing clinical studies and over 10 years of use in Europe with an excellent safety profile.

Is the packaging recyclable?

Enterosgel is committed to reducing its impact on the environment. The plastic tubes are recyclable and the outer packaging is recyclable and is Forest Stewardship Council (FSC) approved. The manufacturer is committed towards exchanging the sachets to a recyclable option.

What does Enterosgel taste like?

Enterosgel is a tasteless gel which when mixed with water forms a slightly opaque liquid, which people find tolerable and easy to drink.

For children with acute diarrhoea it can be mixed with oral rehydration solution instead of water.

What are the latest treatments for IBS in 2025?

Although there have been some trials in recent years for previous IBS therapies such as CBT and low dose amitriptyline. There have been no new treatments in the UK for IBS-D since Enterosgel was shown to be an effective treatment in its trial from 2022 and it was added to the NHS Prescription Drug Tariff.
The Enterosgel trial was published in the leading journal “GUT”, and showed that Enterosgel significantly improved diarrhoea, pain, bloating and urgency in IBS-D patients compared to a placebo group.

How to use ENTEROSGEL®?

How to use Enterosgel?

For Children under 1 year*: 2.5g (½ teaspoon) diluted in 7.5-15ml of water.

For children 1-6 years old*: 5g (1 teaspoon or 1/3 of a sachet) diluted in 50-100ml of water 3 times a day.

For children 7-14 years old: 10g (2 teaspoons or 2/3 of a sachet) diluted in 50-100 ml of water 3 times a day.

For children 15+ and adults: 15-22.5g (1-1½ tablespoon or 1-1½ sachets) diluted in 200ml of water 3 times a day.

*Prior to use in children under 3 years old it is advisable to consult a doctor.

At the start of treatment, you can double the first dose and then continue with the single dose after each bowel movement from 3 to 6 times a day. Maximum 8 doses on the first day. Continue taking an Enterosgel dose 1 to 3 times a day during the following 3-4 days until your bowel movements return to normal.

 

In children and adults, treatment of diarrhoea should also replace lost fluids, this may include use of an oral rehydration solution.

How to treat IBS with diarrhoea (IBS-D) with Enterosgel?

For children 7-14 years old: 2 teaspoons (10g) or 2/3 of a sachet diluted in 50-100 ml of water 3 times a day

For children 15+ and adults: 15-22.5g (1-1½ tablespoons or 1-1½ sachets) diluted in 200ml of water 3 times a day.

During treatment of IBS with diarrhoea you may adjust your dosage to suit your stool consistency and bowel movements. You can increase treatment to a double dose up to 3 times a day if your stool is loose or reduce to a single dose once a day if your stool is normal. Maximum 6 doses per day.

We recommend that you start taking Enterosgel 2-3 times per day for 2-3 weeks to see how Enterosgel can help you manage your IBS-D, then tailor your dose to your daily symptoms.

How to treat Acute Diarrhoea with Enterosgel?

Dose:
For children under 1 years old: 1/2 teaspoon diluted in 7.5-15ml of water 3 times a day

For children 1-6 years old: 1 teaspoon (5g) or 1/3 of a sachet diluted in 50-100ml of water 3 times a day
For children 7-14 years old: 2 teaspoons (10g) or 2/3 of a sachet diluted in 50-100 ml of water 3 times a day
For children 15+ and adults: 1-1.5 tablespoon (15-22.5g) or 1-1.5 sachet diluted in 200ml of water 3 times a day.

At the start of treatment, you can double the first dose and then continue with the single dose after each bowel movement from 3 to 6 times a day. Maximum 8 doses on the first day. Continue taking an Enterosgel dose 1 to 3 times a day during the following 3-4 days until your bowel movements return to normal.

Prior to use in children under 3 years old it is advisable to consult a doctor.

In children and adults, treatment of diarrhoea should also replace lost fluids, this may include use of an oral rehydration solution. Enterosgel can be mixed in oral rehydration solution instead of water.

What are contraindications for taking Enterosgel?

Do not use Enterosgel if you are currently taking modified-released orally administrated medications, or if you have intestinal atony or intestinal blockage (severe constipation due to bowel obstruction)

Can I take with other oral Medications?

Enterosgel does not contain any active pharmaceutical ingredients and can be used alongside other treatments. It is recommended to take Enterosgel 2 hours before or after taking other medications. However, do not take Enterosgel if you are currently taking modified-released orally administrated medications.

Can I take long-term?

Enterosgel can be taken in the longer term. Enterosgel can be taken continuously for 30 day course followed by a short break of 3 days, before starting another course.

Should I take Enterosgel with food?

No, Enterosgel should not be taken with meals, it is best to leave a 1-2 hour gap
between meals and taking Enterosgel.

What happens if I miss a dose?

The recommended daily dose is dependent on your bowel movements and symptoms. If you miss a dose you can take it as soon as you remember, we advise that you follow the dose listed in the Instructions for use.

What it the shelf life of Enterosgel?

Enterosgel has a shelf life of 3 years in the unopened tube or sachet. Once the tube is opened it can be used for 30 days, please keep the lid of the tube tightly closed in between use. Sachets are single use and should be used immediately after opening.

Do I need to store Enterosgel in the fridge?

No, Enterosgel should not be stored in the fridge but at a temperature of between 4-30°C and away from direct sunlight. It is composed of organic mineral and doesn’t contain any ingredients of animal or plant origin that may require storing in a fridge.

How should I store Enterosgel?

Enterosgel should be stored at room temperature (4-30°C), away from direct sunlight and sources of heat.

Who Can Use ENTEROSGEL®?

Can Enterosgel be taken by children?

Yes, Enterosgel is safe for children from 0+ years upwards (newborns) and is well-tolerated by children as it is tasteless. Enterosgel has an excellent tolerability and safety record during 30 years of use. There have been no reports of severe side effects. The clinical studies in children have shown the effectiveness and safety of the product. For children under 3 years old it is advisable to consult a doctor prior to use of Enterosgel.

For treating acute diarrhoea in children Enterosgel can be mixed with oral rehydration solution instead of water.

Can Enterosgel be taken during pregnancy and while breastfeeding?

Yes, Enterosgel is a drug-free mineral gel, which is not absorbed into the body and doesn’t contain any preservatives, so Enterosgel is suitable for pregnant and breastfeeding women. We recommend that you consult your doctor before taking Enterosgel and it is always important to consult with your GP or midwife if you are unwell during pregnancy or breastfeeding.

Can I take Enterosgel if I have food allergies or food intolerance?

Often patients with IBS also suffer from food allergies or food intolerance. Enterosgel is non-allergenic, free from preservatives, gluten, sugar and any additives! Enterosgel can be used to treat diarrhoea in patients caused by food allergies or food intolerance.

Can take Enterosgel if I am diagnosed with coeliac and suffer from diarrhoea and bloating?

Enterosgel is suitable for people with coeliac disease who have acute diarrhoea (short-term). Enterosgel does not treat the coeliac disease itself, but it can help relieve the symptoms of diarrhoea. Enterosgel also adsorbs harmful substances that can lead to the build-up of gases and can thereby help relieve bloating

Can I take enterosgel if I have diabetes?

Yes, Enterosgel can be taken by patients with diabetes. Enterosgel does not contain any sugar.

Is Enterosgel suitable for vegans?

Enterosgel does not contain any ingredients of an animal origin or products produced from animals. Therefore, Enterosgel is suitable for both vegans and vegetarians.

Can I use Enterosgel for other conditions apart from acute diarrhoea or IBS-D?

Enterosgel is currently indicated for the treatment of acute diarrhoea and medically diagnosed IBS-diarrhoea. We recommend that you speak to your doctor before taking Enterosgel for the treatment of other types of chronic diarrhoea or other medical conditions. Enterosgel is not contraindicated for use in any conditions apart from intestinal atony or intestinal blockage.

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