Weight-Loss Jab Diarrhoea (Mounjaro®, Wegovy®, Ozempic®)

Why diarrhoea happens

GLP-1 receptor agonists such as Mounjaro® (tirzepatide), Wegovy®, and Ozempic® (semaglutide) are breakthrough weight-loss injections. But while they control appetite and help reduce body weight, they frequently trigger gastrointestinal side effects. Clinical data shows around 30–35% of patients experience diarrhoea, sometimes lasting up to 48 hours after the jab.

This happens because GLP-1 drugs slow stomach emptying and alter gut motility. They also change bile acid flow and may irritate the gut lining — resulting in loose stools, bloating, and bathroom urgency.

The lived experience

On Reddit and Facebook support groups, patients describe being “stuck at home the day after every jab” and “planning life around the toilet.” Others report fatigue, embarrassment, and anxiety about going to work or eating socially. The diarrhoea is usually not painful, but the unpredictability is debilitating.

ENTEROSGEL®: a safe, drug-free solution

ENTEROSGEL® is an oral intestinal adsorbent (enterosorbent) that works by binding and adsorbing irritants, bile acids, and inflammatory molecules in the gut, then removing them naturally.

⚛︎ Acts like a clever sponge, soaking up substances that trigger diarrhoea.
⚛︎ Drug-free, tasteless, and suitable for long-term use alongside weight-loss jabs.
⚛︎ Safe for all ages, including newborns, pregnancy and breastfeeding — unlike loperamide, which is restricted in children and not recommended in pregnancy.

Case Study: Jessica’s Transformation (Trustpilot)

“Mounjaro has literally transformed my life. It’s amazing, but the diarrhoea side effect had me questioning whether it was worth it. The day after my jab, I’d have diarrhoea for 8–12 hours, sometimes up to 48. I began taking Enterosgel the night before and every few hours on jab day. I’ve noticed such an improvement — last week I had no diarrhoea at all.”

Jessica continues to use ENTEROSGEL® as a pre- and post-jab routine, giving her confidence to continue her weight-loss journey without fear of being housebound.

Quality of life restored

With ENTEROSGEL®, patients:

⚛︎ regain social confidence (dinners, work events, travel),
⚛︎ reduce anxiety about the toilet,
⚛︎ and enjoy a normal diet without extreme restrictions.

Instead of compromising their lives for the sake of treatment, they can continue their weight-loss programme with freedom and dignity.

Start Your Diarrhoea Treatment Today