IBS: Symptoms, Causes, and How ENTEROSGEL® Can Help

1) Understanding IBS

Irritable Bowel Syndrome (IBS) is one of the most common gut conditions, affecting around 10–15% of people in the UK. While some experience only mild symptoms, for many IBS is severe and life-changing. It can control daily life, disrupt work, affect relationships, and cause high levels of stress and anxiety.

IBS is not “just stress” or “in your head.” It is a recognised disorder of gut–brain interaction, with measurable changes in the gut and nervous system that explain why symptoms are so real and often so intense.

2) Symptoms and Diagnosis of IBS

The hallmark symptoms of IBS include:

⚛︎ Abdominal pain and cramping
⚛︎ Diarrhoea, constipation, or a mix of both
⚛︎ Bloating, gas, and discomfort
⚛︎ Urgency — rushing to the toilet, sometimes with fear of accidents
⚛︎ A sensation of incomplete emptying

Doctors diagnose IBS based on symptoms, once other conditions such as coeliac disease or inflammatory bowel disease (IBD) are ruled out. For many patients, the frustrating part is being told all their tests are “normal” while they still live with debilitating symptoms.

Physiological Causes of IBS

Research has identified several biological changes in the gut that contribute to IBS:

⚛︎ Immune activation: low-grade inflammation in the gut lining.
⚛︎ Microbiome imbalance: changes in gut bacteria and how they interact with the body.
⚛︎ Visceral hypersensitivity: over-sensitive gut nerves that send amplified pain and urgency signals to the brain.
⚛︎ Altered motility: bowel movements may be too fast (leading to diarrhoea) or too slow (causing constipation).

These physiological changes explain why IBS is a genuine medical condition and why symptoms persist for years if untreated.

Severity and Impact of IBS:

IBS can range from inconvenient to completely debilitating. Severe IBS-D (diarrhoea-predominant IBS) can mean going to the toilet 10–20 times per day. This leads to:

⚛︎ Fatigue and poor sleep
⚛︎ Anxiety and depression
⚛︎ Missed work and social withdrawal
⚛︎ Restricted diets, fear of eating out, or fear of travel

For many, the burden of IBS is equivalent to living with a chronic condition like diabetes or heart disease.

Potential Causes and Triggers of IBS:

IBS often begins after a trigger event that changes the gut permanently, such as:

⚛︎ A gut infection (known as post-infectious IBS, affecting around 1 in 10 after severe gastroenteritis).
⚛︎ Surgery, which can disrupt gut and immune function.
⚛︎ Medications that affect digestion.
⚛︎ Food sensitivities (certain foods worsen bloating, pain, or diarrhoea).
⚛︎ Stress and anxiety — not the cause of IBS, but often worsening existing symptoms.

ENTEROSGEL®: The Breakthrough Treatment for IBS-D

For decades, IBS sufferers were told to “manage stress,” change their diet, or take medicines that only mask symptoms — such as loperamide, which slows the bowel but does not treat urgency, bloating, or pain.

ENTEROSGEL® changes that.

⚛︎ It is an oral intestinal adsorbent (enterosorbent).
⚛︎ It works by binding and removing harmful substances in the gut — including bacterial toxins, bile acids, and inflammatory molecules.
⚛︎ Unlike symptom-masking drugs, ENTEROSGEL® helps address the underlying causes of diarrhoea and urgency.
⚛︎ Safe from newborns to adults, and suitable during pregnancy and breastfeeding.
⚛︎ Non-allergenic, tasteless, free from gluten, lactose, preservatives, colouring, or sugar.

Clinical Evidence: The Relieve-IBS-D Study showed that ENTEROSGEL® significantly improved:

⚛︎ Stool frequency and consistency
⚛︎ Urgency
⚛︎ Abdominal pain and bloating
⚛︎ Overall quality of life

Patients reported eating more freely, reducing their need for other medications, travelling with confidence, and living without constant anxiety about the toilet.

ENTEROSGEL® is widely available from Boots, Amazon, and independent pharmacies.

IBS is a real medical condition with real impact. It is not just in the mind, and it is not something to “live with.”

With ENTEROSGEL®, patients now have a safe, drug-free, evidence-based treatment that can stop diarrhoea, reduce urgency, ease bloating, and help them return to normal life.

Available on NHS and over the counter at Boots, Amazon, and pharmacies nationwide.

Start Your Treatment Now

4-Weeks IBS Treatment Plan